Microchimerism and allogeneic transplantation
نویسندگان
چکیده
منابع مشابه
Microchimerism and Renal Transplantation: Doubt Still Persists
Background: The Presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. However, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. Objective: To study microchimerism in a group of kidney transplant recipi...
متن کاملMicrochimerism and renal transplantation: doubt still persists.
OBJECTIVE We sought to study microchimerism in a group of kidney transplant recipients. MATERIALS AND METHODS In this study, the peripheral blood microchimerism (PBM) after renal transplantation was retrospectively evaluated in 32 male-to-female recipients of living unrelated or cadaveric donor renal transplants. Using a nested polymerase chain reaction (PCR) amplification specific for SRY re...
متن کاملMicrochimerism, dendritic cell progenitors and transplantation tolerance.
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host. It has been postulated that in chimeric graft recipients, reciprocal modulation of immune responsiveness between donor and recipient leukocytes may lead, eventually, to the induction of...
متن کاملMicrochimerism in renal transplantation – single centre experience
A. Moise, R. D. Sinescu, I. Constantinescu, I. Sinescu 1 Centrul de Imunogeneticæ øi Virusologie, Institutul Clinic „Fundeni”, Bucureøti 2 Universitatea de Medicinæ øi Farmacie „Carol Davila”, Bucureøti 3 Compartimentul de Chirurgie Plasticæ Microchirurgie Reconstructivæ, Spitalul Universitar de Urgenflæ „Elias”, Bucureøti 4 Centrul de Uronefrologie øi Transplant Renal, Institutul Clinic „Funde...
متن کاملmicrochimerism and renal transplantation: doubt still persists
background: the presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. however, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. objective: to study microchimerism in a group of kidney transplant recipi...
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ژورنال
عنوان ژورنال: Chimerism
سال: 2013
ISSN: 1938-1956,1938-1964
DOI: 10.4161/chim.24358